COMING SOON...
Botox® for Depression
in conjunction with conventional therapy
At Horizon Behavioral Health, we are committed to offering innovative, evidence-based treatments to help our patients achieve lasting relief from mood disorders. One emerging option is the use of Botox® (onabotulinumtoxinA) as an adjunctive treatment for depression.
Originally developed for medical and cosmetic uses, Botox has also been shown in multiple clinical studies to help improve symptoms of depression—particularly when injected into the small muscles between the eyebrows (the “glabellar” area). This is thought to work by interrupting the facial expressions that reinforce negative emotions, as well as by influencing brain regions involved in mood regulation.
How it works
- A series of tiny injections in the glabellar area, completed in just a few minutes.
- Most patients begin to notice improvement within 2–4 weeks, with peak effects at about 6 weeks.
- Benefits typically last 2–3 months, after which treatment can be repeated.
Why consider Botox?
- Low systemic side effects – does not affect the rest of the body like many oral medications.
- Quick procedure with no downtime.
- Can be safely combined with therapy, medication, TMS, and Spravato®.
Important to know
Botox for depression is considered an off-label use, meaning it is not FDA-approved for this specific purpose. We follow strict screening, informed consent, and outcome tracking to ensure patient safety and effectiveness. Botox for depression is not covered by insurance.
If you are living with depression that has not fully improved with traditional treatments, you may be a candidate for this innovative approach.
Botox® for Depression
Research shows that Botox®—when injected into the small “frown” muscles—has been associated with improved mood in people with depression. It is believed to work by reducing negative facial expressions and influencing brain pathways involved in mood regulation.
- Fast: 5–10 min procedure
- Onset: 2–4 weeks; peak at 6 weeks
- Duration: 2–3 months
- Low side effects: This is an off-label treatment. We provide careful screening, informed consent, and track your results.
