
Fast-Acting Relief From Depression With SPRAVATO® Therapy – Find Hope Today
SPRAVATO is the brand name for esketamine, a medication used to treat treatment-resistant depression. It is administered as a nasal spray and can be effective in reducing symptoms of depression, even in patients who have not responded to other forms of treatment. Let’s explore what SPRAVATO is, how it works, and its potential benefits and risks.
Rapid Relief
SPRAVATO can provide relief in just a few hours, making it ideal for individuals who need immediate help managing their depression.
Improved Mood
In addition to providing quick relief, many individuals notice improved overall mood and sense of well-being after undergoing SPRAVATO treatment.
Reduction in Suicidal Thoughts
For those struggling with depression, persistent suicidal thoughts can be a constant struggle. SPRAVATO has been shown to help reduce these thoughts and improve overall mental health.

Minimal Side Effects
Many individuals who have undergone SPRAVATO treatment report minimal side effects, making it a more comfortable and manageable treatment option.
Personalized Dosing
With SPRAVATO, the dosage can be personalized to each individual’s needs, ensuring that they are receiving the most effective treatment for their depression.
Long-Lasting Effects
Studies have shown that the effects of SPRAVATO treatment can last for weeks or even months, giving clients a longer period of relief from their depression symptoms.
FAQs
SPRAVATO (esketamine) CIII nasal spray is a derivative of ketamine. SPRAVATO is an FDA-approved nasal spray for treatment-resistant depression; it is also approved to treat depressive symptoms in adults with major depressive disorder with suicidal thoughts or actions. The FDA has not approved ketamine to treat depression. Both SPRAVATO and ketamine are Schedule III controlled substances under the US Controlled Substances Act.
You cannot take SPRAVATO on your own. You will administer SPRAVATO nasal spray yourself in our office. Because of the risks for sedation or loss of consciousness, dissociation, respiratory depression, and abuse and misuse, SPRAVATO can only be administered at healthcare settings certified in the SPRAVATO Risk Evaluation and Mitigation Strategy (REMS) Program.
Do NOT take SPRAVATO if any of the following apply to you:
- You are allergic to esketamine, a similar medicine called ketamine used for anesthesia, or any of the other ingredients in SPRAVATO.
- You have a blood vessel disease (aneurysm), an abnormal connection between your blood vessels (arteriovenous malformation), or a history of bleeding in the brain.
- Be sure to tell your healthcare provider if you have heart, brain, or liver problems; if you have psychosis; or if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed. You should not take SPRAVATO if you are pregnant. You should not breastfeed if you are taking SPRAVATO.
- Tell your healthcare provider about all the medicines that you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
At each visit, we will ask about your symptoms of depression, side effects, and whether or not you are experiencing noticeable improvement. In the clinical studies of SPRAVATO, a standardized scale called the Montgomery-Åsberg Depression Rating Scale was used to track treatment-resistant depression symptoms and response to treatment.
The most common side effects of SPRAVATO are dizziness, headache, nausea, and sleepiness. These usually go away after a few days as your body adjusts to the medication, but you will still need to adhere to a 24-hour supervision period following each dose.
SPRAVATO can also cause dissociation, which is when you feel disconnected from your body or surroundings. This can include feeling out of control, floating, or like you are in a dream. These effects usually go away after the medication wears off, but they can make it hard to drive or operate machinery. For this reason, you will need to have someone drive you home after your first dose of SPRAVATO and after each dose for at least 24 hours.
